140640-91-1

Basic information

• Product Name: METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLATE
• Synonyms: METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLATE
• CAS NO: 140640-91-1
• Molecular Formula: C₁₈H₁₇FN₂O₂
• Molecular Weight: 312.34
• Mol File: 140640-91-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 478.5±45.0 °C(Predicted)
• Appearance: /
• Density: 1.24±0.1 g/cm3(Predicted)
• PKA: 5.86±0.40(Predicted)
• CAS DataBase Reference: METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLATE(140640-91-1)
• EPA Substance Registry System: METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLATE(140640-91-1)

Safety Data

• Hazardous Substances Data: 140640-91-1(Hazardous Substances Data)

Downstream Products

• 853182-23-7 methyl 4-(4-fluorophenyl)-6-(1-methylethyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 

Relevant articles and documents

HMG-COA REDUCTASE INHIBITORS AND METHOD

Compounds are provided having the following structure (I) and pharmaceutically acceptable salts thereof, A is (II) or (III); wherein R1, R2, R3, R4, U, V, W, Y, and n are as defined above, which compounds are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperlipidemia, dyslipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosis as well as Alzheimer's disease and osteoporosis and may be employed as hormone replacement therapy. A method for treating the above diseases employing the above compounds is also provided.