140666-28-0Relevant academic research and scientific papers
Palladium-Catalyzed Allenamide Carbopalladation/Allylation with Active Methine Compounds
Zhu, Xiaoyi,Li, Ruibo,Yao, Hequan,Lin, Aijun
, p. 4630 - 4634 (2021/06/28)
A palladium-catalyzed allenamide carbopalladation/allylation with active methine compounds has been developed. Various indoles and isoquinolinones bearing a quaternary carbon center were achieved with good efficiency, a broad substrate scope and good functional group tolerance. This reaction underwent cascade oxidative addition, carbopalladation, and allylic alkylation, and two new C-C bonds were formed in one pot.
Indole acetyl imino sulfone series compound and preparation method thereof
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Paragraph 0030; 0034-0098, (2021/07/28)
The invention provides an indole acetyl imino sulfone series compound and a preparation method thereof. According to the preparation method, by taking ortho-halogen substituted arylamine, propargyl halide and sulfoxide sulfimide as reaction substrates, re
Asymmetric Domino Heck/Dearomatization Reaction of β-Naphthols to Construct Indole-Terpenoid Frameworks
Wang, Dong-Chao,Cheng, Peng-Peng,Yang, Ting-Ting,Wu, Pan-Pan,Qu, Gui-Rong,Guo, Hai-Ming
supporting information, p. 7865 - 7872 (2021/10/20)
A palladium-catalyzed enantioselective Heck cyclization/dearomatization cascade via capturing the cyclized Heck π-allylpalladium intermediate by β-naphthols is reported, which provides a new strategy for the construction of chiral indole-terpenoid framewo
Tris(trimethylsilyl)silane and visible-light irradiation: A new metal- and additive-free photochemical process for the synthesis of indoles and oxindoles
Da Silva, Gustavo Piva,Ali, Akbar,Da Silva, Rodrigo César,Jiang, Hao,Paix?o, Márcio W.
, p. 15110 - 15113 (2015/10/12)
A combined tris(trimethylsilyl)silane and visible-light-promoted intramolecular reductive cyclization protocol for the synthesis of indoles and oxindoles has been developed. This straightforward and efficient method shows tolerance towards a broad spectru
An approach to cyclohepta[ b ]indoles through an allenamide (4 + 3) cycloaddition-grignard cyclization-chugaev elimination sequence
He, Shuzhong,Hsung, Richard P.,Presser, William R.,Ma, Zhi-Xiong,Haugen, Bryan J.
, p. 2180 - 2183 (2014/05/06)
A strategy for synthesizing highly functionalized cyclohepta[b]indoles through a concise (4 + 3) cycloaddition-cyclization-elimination sequence is described. The cycloaddition features nitrogen-stabilized oxyallyl cations derived from epoxidations of N-ar
Carbolithiation of chloro-substituted alkynes: A new access to vinyl carbenoids
Lhermet, Rudy,Ahmad, Maha,Fressigne, Catherine,Silvi, Bernard,Durandetti, Muriel,Maddaluno, Jacques
, p. 10249 - 10254 (2014/08/18)
The intramolecular carbolithiation of a series of chloro-substituted alkynes leads to exocyclic alkylidene carbenoids of which both nucleophilic and electrophilic characters can be drove. A sole stereoselective 5-exo-dig addition takes place, probably bec
A strategy for the synthesis of 2,3-disubstituted indoles starting from N-(o-halophenyl)allenamides
Fuwa, Haruhiko,Sasaki, Makoto
, p. 2214 - 2218 (2008/03/14)
A strategy for the synthesis of 2,3-disubstituted indole derivatives based on an intramolecular carbopalladation-anion capture cascade has been developed, wherein construction of the pyrrole ring and functionalisation of the indole C2 and C3 positions wer
CONVERSION OF 2-IODOANILINE INTO (Z)-3-METHYLENE-2,3-DIHYDROINDOLE DERIVATIVES
Luo, Fen-Tair,Wang, Ren-Tzong
, p. 2365 - 2372 (2007/10/02)
Treatment of N-(2-iodophenyl)-N-2-propynyl-p-tolylsulfonamide with various organozinc chlorides in the presence of palladium acetate, triphenylphosphine, and 1 equiv. of triethylamine in tetrahydrofuran gives (Z)-3-alkylidene-2,3-dihydroindoles via intramolecular Heck-type reaction and successive cross coupling reactions.
