140675-42-9

Basic information

• Product Name: 3',5'-DIFLUORO-2'-HYDROXYACETOPHENONE
• Synonyms: 1-(3,5-DIFLUORO-2-HYDROXYPHENYL)ETHAN-1-ONE;3',5'-DIFLUORO-2'-HYDROXYACETOPHENONE;3,5-DIFLUORO-2-HYDROXYACETOPHENONE;3,5-DIFLUOROSALICYLALDEHYDE;3',5'-Difluoro-2'-hydroxyacetophenone 98%;3',5'-Difluoro-2'-hydroxyacetophenone98%;1-(3,5-Difluoro-2-hydroxyphenyl)ethanone;1-(3,5-Difluoro-2-hydroxyphenyl)ethan-1-one, 2-Acetyl-4,6-difluorophenol
• CAS NO: 140675-42-9
• Molecular Formula: C₈H₆F₂O₂
• Molecular Weight: 172.13
• Product Categories: Aromatic Acetophenones & Derivatives (substituted)
• Mol File: 140675-42-9.mol

Chemical Properties

• Melting Point: 53-55°C
• Boiling Point: 220.8 °C at 760 mmHg
• Flash Point: 87.3 °C
• Appearance: /
• Density: 1.346 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.93±0.23(Predicted)
• CAS DataBase Reference: 3',5'-DIFLUORO-2'-HYDROXYACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-DIFLUORO-2'-HYDROXYACETOPHENONE(140675-42-9)
• EPA Substance Registry System: 3',5'-DIFLUORO-2'-HYDROXYACETOPHENONE(140675-42-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 140675-42-9(Hazardous Substances Data)

Usage

Preparation

3',5'-DIFLUORO-2'-HYDROXYACETOPHENONE can be easily obtained by Fries rearrangement of 2,4-difluorophenyl acetate with aluminium chloride without solvent at 150°, and purified by recrystallization from ethanol (80–90%) ; the 2,4-difluorophenyl acetate is prepared by reaction of acetic anhydride on 2,4-difluorophenol.

Upstream product

• 36914-77-9 acetic acid 2,4-difluorophenyl ester 
• 551002-42-7 4,6-difluoro-2-iodo-phenol 
• 367-27-1 2,4-difluorophenol 

Downstream Products

• 147300-09-2 3,5-difluorobenzene-1,2-diol 
• 1333240-81-5 C₂₄H₁₆F₂N₂O₂ 
• 1333240-91-7 C₂₄H₁₃ClF₂N₂O₂ 
• 1333240-92-8 C₂₄H₁₂BrClF₂N₂O₂ 
• 1333240-82-6 C₂₄H₁₅BrF₂N₂O₂ 
• 1333240-93-9 C₂₄H₁₂Cl₂F₂N₂O₂ 
• 1333240-83-7 C₂₄H₁₅ClF₂N₂O₂ 
• 1333240-94-0 C₂₄H₁₂ClF₃N₂O₂ 
• 1333240-84-8 C₂₄H₁₅F₃N₂O₂ 
• 1333240-95-1 C₂₅H₁₅ClF₂N₂O₂ 
• 1333240-85-9 C₂₅H₁₈F₂N₂O₂ 
• 1192815-24-9 C₈H₅BrF₂O₂ 
• 1193392-90-3 2,4-difluoro-6-methoxyphenol 

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