140685-80-9 Usage
Molecular weight
213.68 g/mol (with hydrochloride)
Appearance
Crystalline solid or white powder
Solubility
Soluble in water, slightly soluble in ethanol, and insoluble in nonpolar solvents
Stability
Stable under normal temperature and pressure, sensitive to light and heat
Derivative of
Phenylalanine (an amino acid)
Functional groups
Amino group (-NH2), hydroxyl group (-OH), and a methyl group (-CH3) attached to the phenyl ring
Use
Pharmaceutical and research applications, synthesis of pharmaceuticals, and biochemical research
Bioactive properties
Potential role in drug development and as a research tool in biochemistry and pharmacology
Chemical structure importance
Valuable for studying the effects and mechanisms of action of different drugs and compounds in biological systems
Salt form
Hydrochloride (HCl) salt, which increases solubility and stability in aqueous solutions
Polarity
Polar due to the presence of the hydroxyl and amino groups, as well as the hydrochloride counterion
Reactivity
Can undergo reactions such as acylation, alkylation, and nucleophilic substitution due to the presence of reactive functional groups
Check Digit Verification of cas no
The CAS Registry Mumber 140685-80-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,6,8 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 140685-80:
(8*1)+(7*4)+(6*0)+(5*6)+(4*8)+(3*5)+(2*8)+(1*0)=129
129 % 10 = 9
So 140685-80-9 is a valid CAS Registry Number.
140685-80-9Relevant academic research and scientific papers
Synthesis and aldose reductase inhibitory activities of benzyl-2-oxazolecarbamate analogues
Miyahara,Kasugai,Ohmomo,Tanaka,Tanimoto
, p. 245 - 248 (2007/10/02)
Various analogues of benzyl 5-phenyl-2-oxazolecarbamate (1a) were synthesized, and the structure-activity relationship of these analogues as aldose reductase inhibitor was studied. The carbamate group was necessary for the inhibitory activity. The introduction of an alkyl group at the C-4 position of 1a enhanced the inhibitory activity, however, the N-carboxymethyl group on the carbamate moiety counteracted to a hydrophobic interaction between the alkyl group at the C-4 position and the enzyme molecule.
