140692-93-9

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5-methyl[1,6]naphthyridine serves as a crucial building block in the synthesis of various biologically active compounds, including antiviral and antimicrobial agents. Its unique structure and properties make it an essential intermediate for creating diverse pharmacologically active molecules, contributing to the development of new drugs.
Used in Research and Development:
In the realm of research and development, 2-chloro-5-methyl[1,6]naphthyridine is utilized for the discovery of novel drug candidates. Its involvement in the synthesis process aids scientists in exploring and understanding the therapeutic potential of new chemical entities.
Used in Agrochemical Industry:
2-Chloro-5-methyl[1,6]naphthyridine may also be applied in the agrochemical sector, where it can be employed in the synthesis of pesticides and herbicides. Its chemical properties make it a valuable component in developing effective and targeted agrochemical products.

Upstream product

• 88296-61-1 medorinone 
• 1118-66-7 4-amino-3-penten-2-one 
• 5220-65-5 5-acetyl-6-methyl-2(1H)-pyridinone 
• 88877-00-3 5-Acetyl-6-((E)-2-dimethylamino-vinyl)-1H-pyridin-2-one 

Downstream Products

• 1085267-03-3 2-(4-benzylpiperidin-1-yl)-N-(5-methyl[1,6]naphthyridin-2-yl)acetamide 
• 1085267-10-2 1-[2-(4-benzylpiperidin-1-yl)ethyl]-3-(5-methyl[1,6]naphthyridin-2-yl)urea 
• 1085266-43-8 [2-(4-benzylpiperidin-1-yl)ethyl]-(5-methyl[1,6]naphthyridin-2-yl)amine 

Relevant academic research and scientific papers

UROTENSIN II RECEPTOR ANTAGONISTS

Compounds of the formula (I) wherein R1, R2, R3, R4, R5, R6, W, and Y are as described herein, or a tautomer, prodrug, solvate, or salt thereof. These compounds are useful as inhibitors of Urotensin II and are thus useful for treating a variety of disease

Novel cAMP PDE III Inhibitors: 1,6-Naphthyridin-2(1H)-ones

Two series of medorinone (3) analogs were prepared by modifications at C(2) and C(5).The C(2)-series was prepared from 2-chloro-5-methyl-1,6-naphthyridine (4) by replacement of the chloro group with various nucleophiles.The C(5)-series was prepared from 5

Pyridine and related aza heterocycle derivatives as cardiovascular agents

Novel pharmaceutical compounds and compositions having nitrogen containing ring systems which may be represented by the following structural formula: wherein R1 or R3 is a moiety of the formula: wherein R6 is selected from either hydrogen or acetyl; R7 is selected from 2, 3 or 4-pyridyl or 1-imidazolyl and Q is -(CH2)n, where n is an integer from 1 to 5 and R1 and R2, R2 and R3, R3 and R4 or R4 and R5 taken together may be -CH=CH-CH=CH-. The compounds and compositions are useful as inhibitors of thromboxane synthetase and in the treatment of hypertension and arrythmia in mammals.