14070-61-2Relevant academic research and scientific papers
Sulfur(IV)-mediated transformations: From ylide transfer to metal-free arylation of carbonyl compounds
Huang, Xueliang,Patil, Mahendra,Fares, Christophe,Thiel, Walter,Maulide, Nuno
supporting information, p. 7312 - 7323 (2013/06/26)
The development of a direct ylide transfer to carbonyl derivatives and of a sulfoxide-mediated arylation is presented from a unified perspective. Mechanistic studies (including density functional calculations) support a common reaction pathway and showcase how subtle changes in reactant properties can lead to disparate and seemingly unrelated reaction outcomes.
Sulfoxide-mediated α-arylation of carbonyl compounds
Huang, Xueliang,Maulide, Nuno
scheme or table, p. 8510 - 8513 (2011/07/09)
A novel sulfoxide-mediated α-arylation of carbonyl compounds is reported. This reaction proceeds under very mild conditions at room temperature and does not require any transition-metal promoter or catalyst.
A direct ylide transfer to carbonyl derivatives and heteroaromatic compounds
Huang, Xueliang,Goddard, Richard,Maulide, Nuno
supporting information; experimental part, p. 8979 - 8983 (2011/02/24)
Power transfer: The title reaction proceeds under mild conditions (room temperature, short reaction times) and directly affords sulfonium ylides from active methylene compounds and heteroaromatics in a single step and in high yields. A detailed comparative structural analysis of a variety of ylides is presented and the implications of structure on the reactivity of these compounds are discussed.
