140709-90-6Relevant academic research and scientific papers
Ligand Control of Palladium-Catalyzed Site-Selective α- and γ-Arylation of α,β-Unsaturated Ketones with (Hetero)aryl Halides
So, Chau Ming,Yuen, On Ying
, p. 23438 - 23444 (2020)
This study describes the first palladium-catalyzed, site-selective α- and γ-arylation of α,β-unsaturated ketones with (hetero)aryl halides. A wide range of hetero(aryl)halides coupled with α,β-unsaturated ketones, and transformation into the arylated products proceeded with excellent to good yields. The site selectivity of the reaction is switchable by simply changing the phosphine ligand to access either α-arylated or γ-arylated products in good to excellent yields by using a low catalyst loading, and the method demonstrates good functional-group compatibility.
Combined Dynamic Kinetic Resolution and C?H Functionalization for Facile Synthesis of Non-Biaryl-Atropisomer-Type Axially Chiral Organosilanes
Li, Zhao,Wang, Xu,Cui, Yu-Ming,Ma, Jun-Han,Fang, Li-Lei,Han, Lu-Lu,Yang, Qin,Xu, Zheng,Xu, Li-Wen
, p. 4336 - 4340 (2021)
Although asymmetric C?H functionalization has been available for the synthesis of structurally diverse molecules, catalytic dynamic kinetic resolution (DKR) approaches to change racemic stereogenic axes remain synthetic challenges in this field. Here, a c
Modified stille coupling utilizing α-iodoenones
Johnson,Adams,Braun,Senanayake
, p. 919 - 922 (2007/10/02)
α-Iodoenones undergo Pd-catalyzed coupling with alkenyl- and aryltributylstannanes providing an efficient route to the corresponding α-substituted enones.
