140715-56-6

Basic information

• Product Name: 2-(3-BROMOPROPYL)-5-NITROISOINDOLINE-1,3-DIONE
• Synonyms: 2-(3-BROMOPROPYL)-5-NITROISOINDOLINE-1,3-DIONE;N-(3-BROMOPROPYL)-4-NITROPHTHALIMIDE;2-(3-Bromopropyl)-5-nitro-1H-isoindole-1,3(2H)-dione, 2-(3-Bromopropyl)-5-nitroisoindoline-1,3-dione;N-(3-Bromoprop-1-yl)-4-nitrophthalimide 97%;2-(3-Bromoprop-1-yl)-5-nitro-1H-isoindole-1,3(2H)-dione, 2-(3-Bromoprop-1-yl)-5-nitroisoindoline-1,3-dione;N-(3-Bromoprop-1-yl)-4-nitrophthalimide97%;2-(3-Bromopropyl)-5-nitro-1H-isoindole-1,3(2H)-dione
• CAS NO: 140715-56-6
• Molecular Formula: C11H9BrN2O4
• Molecular Weight: 313.1
• Mol File: 140715-56-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 104-107
• Boiling Point: 443.1°Cat760mmHg
• Flash Point: 221.8°C
• Appearance: /
• Density: 1.723g/cm³
• Vapor Pressure: 4.76E-08mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 2-(3-BROMOPROPYL)-5-NITROISOINDOLINE-1,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-BROMOPROPYL)-5-NITROISOINDOLINE-1,3-DIONE(140715-56-6)
• EPA Substance Registry System: 2-(3-BROMOPROPYL)-5-NITROISOINDOLINE-1,3-DIONE(140715-56-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 140715-56-6(Hazardous Substances Data)

Usage

General Description

2-(3-Bromopropyl)-5-nitroisoindoline-1,3-dione is a chemical compound that contains a nitro group and a bromopropyl chain attached to an isoindoline-1,3-dione ring system. It is primarily used as a building block in organic synthesis and has potential applications in pharmaceutical and material science research. The presence of the nitro group suggests that it may have antibacterial or antifungal properties, while the bromopropyl chain could make it useful in cross-coupling reactions for the synthesis of more complex molecules. Additionally, the isoindoline-1,3-dione core is commonly found in various bioactive compounds, indicating that this chemical may have pharmacological activity. However, further research is necessary to fully understand the potential uses and properties of 2-(3-Bromopropyl)-5-nitroisoindoline-1,3-dione.

InChI:InChI=1/C11H9BrN2O4/c12-4-1-5-13-10(15)8-3-2-7(14(17)18)6-9(8)11(13)16/h2-3,6H,1,4-5H2

Upstream product

• 89-40-7 4-nitrophthalimide 
• 109-64-8 1,3-dibromo-propane 
• 136918-14-4 phthalimide 

Downstream Products

• 1428332-75-5 C₁₈H₁₇BrN₂O₄S 

Relevant articles and documents

A new series of N2-substituted-5-(p-toluenesulfonylamino)phthalimide analogues as α-glucosidase inhibitors

Several members of a new family of non-sugar-type α-glycosidase inhibitors, bearing a 5-(p-toluenesulfonylamino)phthalimide moiety and various substituent at the N2 position, were synthesized and their activities were investigated. The newly synthesized compounds displayed different inhibition profile towards yeast α-glycosidase and rat intestinal α-glycosidase. Almost all the compounds had strong inhibitory activities against yeast α-glycosidase. Regarding rat intestinal α-glycosidase, only analogs with N2-aromatic substituents displayed varying degrees of inhibitory activities on rat intestinal maltase and lactase and nearly all compounds showed no inhibition against rat intestinal α-amylase. Structure-activity relationship studies indicated that 5-(p- toluenesulfonylamino)phthalimide moiety is a favorable scaffold to exert the α-glucosidase inhibitory activity and substituents at the N2 position have considerable influence on the efficacy of the inhibition activities.