14073-00-8Relevant articles and documents
Visible-Light-Mediated Enantioselective Photoreactions of 3-Alkylquinolones with 4- O-Tethered Alkenes and Allenes
Li, Xinyao,Jandl, Christian,Bach, Thorsten
, p. 3618 - 3622 (2020)
The title compounds undergo intramolecular [2 + 2] photocycloaddition reactions when irradiated with visible light in the presence of a chiral sensitizer. Up to four defined stereogenic centers are formed in a single step (14 examples with a tethered alkene, 6 examples with an allene, 72-99percent yield, 81-99percent ee) at catalyst loadings as low as 0.5 mol percent. The alkyl group in the 3-position is crucial for the success of the reaction as it leads to a significant decrease of the triplet energy.