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  • 1407543-28-5 Structure
  • Basic information

    1. Product Name: C11H14N4O3
    2. Synonyms: C11H14N4O3
    3. CAS NO:1407543-28-5
    4. Molecular Formula:
    5. Molecular Weight: 250.257
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1407543-28-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C11H14N4O3(CAS DataBase Reference)
    10. NIST Chemistry Reference: C11H14N4O3(1407543-28-5)
    11. EPA Substance Registry System: C11H14N4O3(1407543-28-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1407543-28-5(Hazardous Substances Data)

1407543-28-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1407543-28-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,7,5,4 and 3 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1407543-28:
(9*1)+(8*4)+(7*0)+(6*7)+(5*5)+(4*4)+(3*3)+(2*2)+(1*8)=145
145 % 10 = 5
So 1407543-28-5 is a valid CAS Registry Number.

1407543-28-5Upstream product

1407543-28-5Relevant articles and documents

Synthesis and evaluation of 8-amino-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives as glycogen synthase kinase-3 (GSK-3) inhibitors

Chun, Kwangwoo,Park, Ji-Seon,Lee, Han-Chang,Kim, Young-Ha,Ye, In-Hea,Kim, Kang-Jeon,Ku, Il-Whea,Noh, Min-Young,Cho, Goang-Won,Kim, Heejaung,Kim, Seung Hyun,Kim, Jeongmin

, p. 3983 - 3987 (2013)

New potent glycogen synthase kinase-3 (GSK-3) inhibitors, 8-amino-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives, were designed by modeling, synthesized and evaluated in vitro. Compound 17c showed good potency in enzyme and cell-based assays (IC50 = 111 nM, EC50 = 1.78 μM). Moreover, it has demonstrated desirable water solubility, PK profile, and moderate brain penetration.

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