1408006-07-4Relevant academic research and scientific papers
One-pot microwave-assisted synthesis of novel substituted N-dichloroacetyl-4,5-dimethyl-1,3-oxazolidines
Fu, Ying,Yang, Lei,Ye, Fei,Gao, Shuang
, p. 1235 - 1238 (2012)
A one-pot and efficient synthesis of substituted N-dichloroacetyl-4,5- dimethyl-1,3-oxazolidines utilizing the reaction of alkamine with aldehyde or ketone in refluxing benzene under microwave irradiation was described. The N-acylation was followed with dichloroacetyl chloride and NaOH acting as the attaching acid agent. All compounds were characterized by IR, 1H NMR, 13C NMR, and element analysis. Additionally, the absolute configuration of 4a was determined by X-ray crystallography. All the compounds were tested for their herbicide safeners activity of protecting the maize from the injury of acetochlor.
