1408060-23-0Relevant articles and documents
Synthesis and pharmacological evaluation of 4-iminothiazolidinones for inhibition of pi3 kinase
Pinson, Jo-Anne,Frazzetto, Mark,Zheng, Zhaohua,Jennings, Ian G.,Chalmers, David K.,Thompson, Philip E.,Schmidt-Kittler, Oleg,Kinzler, Kenneth W.,Vogelstein, Bert
, p. 1396 - 1404,9 (2020/09/02)
The thiazolidinedione, compound 1, has previously shown pan-inhibition of the phosphoinositide 3-kinase (PI3K) class I isoforms. We hypothesized the derivatization of the thiazolidinedione core of compound 1 could introduce isoform selectivity. We report