1408074-42-9

Basic information

• Product Name: 5-((tert-Butoxycarbonyl)aMino)tetrahydro-2H-pyran-2-carboxylic Acid
• Synonyms: 5-((tert-Butoxycarbonyl)aMino)tetrahydro-2H-pyran-2-carboxylic Acid;5-{[(tert-butoxy)carbonyl]amino}oxane-2-carboxylic acid;5-(Boc-amino)-tetrahydro-pyran-2-carboxylic acid
• CAS NO: 1408074-42-9
• Molecular Formula: C11H19NO5
• Molecular Weight: 245.27226
• Product Categories: Heterocycles, Miscellaneous Reagents
• Mol File: 1408074-42-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-((tert-Butoxycarbonyl)aMino)tetrahydro-2H-pyran-2-carboxylic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-((tert-Butoxycarbonyl)aMino)tetrahydro-2H-pyran-2-carboxylic Acid(1408074-42-9)
• EPA Substance Registry System: 5-((tert-Butoxycarbonyl)aMino)tetrahydro-2H-pyran-2-carboxylic Acid(1408074-42-9)

Safety Data

• Hazardous Substances Data: 1408074-42-9(Hazardous Substances Data)

Usage

Uses

5-((tert-Butoxycarbonyl)amino)tetrahydro-2H-pyran-2-carboxylic Acid

Upstream product

• 603130-12-7 1,5-anhydro-2-[(tert-butoxycarbonyl)amino]-2,3,4-trideoxy-D-erythro-hexitol 
• 125901-90-8 (2R,3S)-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-ol 
• 149342-25-6 ((2R,3S)-3-acetoxy-3,6-dihydro-2H-pyran-2-yl)methyl acetate 
• 132375-36-1 6-O-(tert-butyldimethylsilyl)-1,5-anhydro-2,3-dideoxy-D-erythro-hex-2-enitol 
• 199801-85-9 O-[(2R,3S)-2-(tert-butyldimethylsilyloxymethyl)-3,6-dihydro-2H-pyran-3-yl]trichloroethanecarboximidate 
• 199801-81-5 N-((3R,6S)-6-(((tert-butyldimethylsilyl)oxy)methyl)-3,6-dihydro-2H-pyran-3-yl)-2,2,2-trichloroacetamide 
• 2873-29-2 D-glucal triacetate 
• 603130-11-6 (2S,5R)-5-[(tert-butoxycarbonyl)amino]-2-[(tert-butyldimethylsilanyloxy)methyl]-2,5-dihydro-6H-pyran 
• 603130-24-1 ((3S,6S)-6-Hydroxymethyl-tetrahydro-pyran-3-yl)-carbamic acid tert-butyl ester 
• 273199-64-7 (2R,3R)-2-[(tert-butyldimethylsilanyloxy)methyl]-3-hydroxy-3,6-dihydro-2H-pyran 
• 603130-23-0 (2S,5S)-5-[(tert-butoxycarbonyl)amino]-2-[(tert-butyldimethylsilanyloxy)methyl]-2,5-dihydro-6H-pyran 
• 603130-22-9 N-[6-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl]-2,2,2-trichloro-acetamide 
• 603130-21-8 2,2,2-trichloro-acetimidic acid 2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester 
• 603130-20-7 4-nitro-benzoic acid 2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester 

Relevant articles and documents

MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY

The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1 to R3, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing one or more diseases or disorders associated with integrated stress response.

1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS

A compound of formula (I), wherein R, R1, R2, R3, Y, Y1, a, X, and Z are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne Muscular Dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

TRICYCLIC ANTIBIOTICS

Compounds of formula (I), wherein A1 represents -0-, -S- or -CH2-; A2 represents -CH2- or -0-; A3 represents C3-C8cycloalkylene; saturated or unsaturated 4 to 8-membered heterocyclodiyl with 1, 2 or 3 heteroatoms selected from nitrogen or oxygen, which group A3 is unsubstituted or substituted; A4 represents C1-C4alkylene, -C(=0)-; G represents aryl or heteroaryl, which is unsubstituted or substituted; X1 represents a nitrogen atom or CR1; R1 represents a hydrogen atom or a halogen atom; R2 represents a hydrogen atom; m is 0 or 1; n is 1; the -(CH2)n- group is unsubstituted or substituted; p is 0 or 1; or pharmaceutically acceptable salts thereof are valuable for use as a medicament for the treatment of bacterial infections.