1408237-15-9

Upstream product

• 400710-04-5 1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)but-3-en-1-ol 
• 374749-82-3 (1S,3S)-1'-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)butane-1,3-diol 
• 1408237-14-8 (5S,7R)-5'-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2,7,10,10-pentamethyl-3,3,9,9-tetraphenyl-4,8-dioxa-3,9-disilaundecane 

Downstream Products

• 1408237-16-0 (5R,7S)-2,2,5,10,10-pentamethyl-3,3,9,9-tetraphenyl-7-vinyl-4,8-dioxa-3,9-disilaundecane 

Relevant academic research and scientific papers

Stereoselective total synthesis of stagonolide-C

The highly stereoselective synthesis of a biologically active stagonolide-C has been described. The pivotal functionalities are derived from Barbier allylation, an epoxidation by m-CPBA, a chiral-auxiliary mediated acetate aldol addition, a 1,3-anti-reduction, a Sharpless kinetic resolution, a Yamaguchi macrolactonization, and ring-closing metathesis.