1408252-76-5

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 934762-60-4 (1R,2R)-1-N-(diphenylphosphoryl)cyclohexane-1,2-diamine 
• 1408252-88-9 (1R,2R)-N-[2-(N'-phthaloyl)cyclohexyl]diphenylphosphinic amide 
• 438588-60-4 2-((1R,2R)-2-aminocyclohexyl)isoindoline-1,3-dione 
• 20439-47-8 (1R,2R)-1,2-diaminocyclohexane 

Relevant academic research and scientific papers

Constructing a quantitative correlation between N-substituent sizes of chiral ligands and enantioselectivities in asymmetric addition reactions of diethylzinc with benzaldehyde

Using the asymmetric addition reaction of diethylzinc with benzylaldehyde as a model, we have demonstrated that excellent correlations exist between steric reference parameters (Charton and Sterimol values) for appropriate sets of substituents present on chiral 1,2-amino-phosphoramide ligands and the enantiomeric ratios of alcohol products produced in this process.