1408285-69-7Relevant academic research and scientific papers
Chemoselective cross-coupling reactions with differentiation between two nucleophilic sites on a single aromatic substrate
Linshoeft, Julian,Heinrich, Annika C. J.,Segler, Stephan A. W.,Gates, Paul J.,Staubitz, Anne
supporting information, p. 5644 - 5647 (2013/01/15)
A new thiophene building block, containing both a stannyl group and a boronic ester, was prepared. From this starting material, a general, nucleophile-selective one-pot reaction was developed, exploiting the different reactivities of the Stille and Suzuki-Miyaura cross-coupling reactions. A series of aromatic electrophiles were used to demonstrate the high functional group tolerance.
