1408295-51-1Relevant articles and documents
Enantioselective fluorination of ?-ketoesters catalyzed by chiral sodium phosphate: Remarkable enhancement of reactivity by simultaneous utilization of metal enolate and metal phosphate
Mori, Keiji,Miyake, Ayaka,Akiyama, Takahiko
supporting information, p. 137 - 139 (2014/01/23)
A highly enantioselective fluorination of ?-ketoesters catalyzed by chiral sodium phosphate is achieved. In this process, the simultaneous formation of sodium enolate and sodium phosphate under basic conditions is the key to achieving excellent selectivity. Indanone derivatives as well as benzofuranone derivatives could be employed in this reaction to afford the fluorinated adducts in good yields with good to excellent enantioselectivities.
Recyclable fluorous cinchona alkaloid ester as a chiral promoter for asymmetric fluorination of β-ketoesters
Yi, Wen-Bin,Huang, Xin,Zhang, Zijuan,Zhu, Dian-Rong,Cai, Chun,Zhang, Wei
experimental part, p. 1233 - 1240 (2012/09/21)
A fluorous cinchona alkaloid ester has been developed as a chiral promoter for the asymmetric fluorination of β-ketoesters. It has comparable reactivity and selectivity to the nonfluorous versions of cinchona alkaloids and can be easily recovered from the
