1408318-49-9

Basic information

• Product Name: C₂₅H₄₀N₂O₅
• Synonyms: C₂₅H₄₀N₂O₅
• CAS NO: 1408318-49-9
• Molecular Weight: 448.603
• Mol File: 1408318-49-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₅H₄₀N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₄₀N₂O₅(1408318-49-9)
• EPA Substance Registry System: C₂₅H₄₀N₂O₅(1408318-49-9)

Safety Data

• Hazardous Substances Data: 1408318-49-9(Hazardous Substances Data)

Upstream product

• 62965-35-9 N-tert-butyloxycarbonyl-L-tert-leucine 
• 102124-10-7 tert-butyl 3-(benzylamino)propanoate 

Relevant articles and documents

Solution-phase synthesis of novel seven-membered cyclic dipeptides containing α- And β-amino acids

A convenient synthetic procedure for the preparation of seven-membered cyclic α,β-dipeptides is described. Following coupling of N-protected α-amino acids with N-substituted β-amino acid tert-butyl esters, that affords linear α,β-dipeptides, the protecting groups at the terminal functionalities were removed and the open-chain dipeptides were cyclized with phenylphosphonic dichloride, PhP(O)Cl2, to give the desired cyclic α,β-dipeptides in good yields. NMR studies, X-ray diffraction analysis, and DFT calculations provided evidence for the conformation adopted by these cyclic dipeptides in solution, in the solid-state, and in the gas phase.