1408318-78-4

Basic information

• Product Name: C₁₈H₂₀N₂O₃
• Synonyms: C₁₈H₂₀N₂O₃
• CAS NO: 1408318-78-4
• Molecular Weight: 312.368
• Mol File: 1408318-78-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₀N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₀N₂O₃(1408318-78-4)
• EPA Substance Registry System: C₁₈H₂₀N₂O₃(1408318-78-4)

Safety Data

• Hazardous Substances Data: 1408318-78-4(Hazardous Substances Data)

Upstream product

• 2900-27-8 (2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethanoic acid 
• 102124-10-7 tert-butyl 3-(benzylamino)propanoate 
• 1408318-47-7 C₂₇H₃₆N₂O₅ 
• 63398-31-2 C₁₈H₂₅NO₆ 

Downstream Products

• 1408318-93-3 1-benzyl-3(S)-phenyl-1,4-diazepine-2,5-dione 

Relevant articles and documents

Asymmetric Michael addition organocatalyzed by α,β-dipeptides under solvent-free reaction conditions

The application of six novel α,β-dipeptides as chiral organocatalysts in the asymmetric Michael addition reaction between enolizable aldehydes and N-arylmaleimides or nitroolefins is described. With N-arylmaleimides as substrates, the best results were achieved with dipeptide 2 as a catalyst in the presence of aq. NaOH. Whereas dipeptides 4 and 6 in conjunction with 4-dimethylaminopyridine (DMAP) and thiourea as a hydrogen bond donor proved to be highly efficient organocatalytic systems in the enantioselective reaction between isobutyraldehyde and various nitroolefins.