140836-70-0

Usage

Uses

Used in Pharmaceutical Industry:
[2-(3-Aminomethyl-phenoxy)-ethyl]-dimethyl-amine is used as an intermediate in the synthesis of various organic compounds for the development of new drugs. Its unique structure allows it to serve as a building block for creating a wide range of pharmaceutical products, contributing to the advancement of drug discovery and innovation.
Used in Chemical Industry:
In the chemical industry, [2-(3-Aminomethyl-phenoxy)-ethyl]-dimethyl-amine is utilized as a key component in the production of specialty chemicals. Its ability to form various organic compounds makes it a valuable asset in the synthesis of different chemical products, enhancing the diversity and applicability of chemical substances in various sectors.

Upstream product

• 1242928-95-5 tert-butyl 3-(2-(dimethylamino)ethoxy)benzylcarbamate 
• 500024-50-0 3-(2-(dimethylamino)ethoxy)benzonitrile 
• 140836-71-1 3-<2-(dimethylamino)ethoxy>benzaldoxime 

Downstream Products

• 140836-67-5 N-<3-<2-(dimethylamino)ethoxy>benzyl>-3,4,5-trimethoxybenzamide 
• 1242928-90-0 N³-(3-(2-(dimethylamino)ethoxy)benzyl)-N⁶-(4-chlorophenyl)-1,2,4,5-tetrazine-3,6-diamine 

Relevant academic research and scientific papers

SUBSTITUTED BENZOTRIAZINES AND QUINOXALINES AS INHIBITORS OF P7OS6 KINASE

The invention provides compounds of the formula (1): or salts or tautomers thereof; wherein X1 is N or N+(O ); X2 is N or CH; Q is a C1-3 alkylene group; R1 is selected from hydrogen, C1-4 hydrocarbyl and hydroxy-C2-4 hydrocarbyl; R2, R3 and R4 are the same or different and each is selected from hydrogen, fluorine, chlorine and methyl; Ar1 is an optionally substituted monocyclic 5 or 6-membered aryl or heteroaryl ring containing 0, 1 or 2 heteroatom ring members selected from O, N and S, or a naphthyl ring and Ar2 is an optionally substituted monocyclic 5 or 6-membered heteroaryl ring containing 1, 2 or 3 heteroatom ring members selected from O, N and S. The compounds of formula (1) are inhibitors of p70S6 kinase and are useful in the treatment of proliferative diseases.

Antimalarial 3-arylamino-6-benzylamino-1,2,4,5-tetrazines

We report on novel 3-arylamino-6-benzylamino-1,2,4,5-tetrazines with potent activity against Plasmodium falciparum.

Synthesis, gastrointestinal prokinetic activity and structure-activity relationships of novel N-[[2-(dialkylamino)ethoxy]benzyl]benzamide derivatives

Novel N-[[2-(dialkylamino)ethoxy]benzyl]benzamide derivatives (II-1-51), derived from the structural modification of metoclopramide (1), were synthesized and examined for their pharmacological activities. Among them, N-[4-[2-(dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide (II-34) which exhibited well balanced gastrointestinal prokinetic and antiemetic activities was selected as a new type of gastrointestinal prokinetic agent.