140837-98-5 Usage
General Description
"Z-N-Me-D-Glu(OtBu)-OH" is a chemical compound consisting of a Z protecting group attached to a N-methylated derivative of D-glutamate with an O-tert-butyl ester on the carboxylic acid group. Z-N-Me-D-Glu(OtBu)-OH is often used in research and drug development due to its potential pharmacological properties and ability to act as a building block for more complex molecules. The Z protecting group is commonly used in peptide synthesis to protect the amine group, while the tert-butyl ester helps to increase the compound's stability. Overall, "Z-N-Me-D-Glu(OtBu)-OH" is a versatile and valuable component in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 140837-98-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,8,3 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 140837-98:
(8*1)+(7*4)+(6*0)+(5*8)+(4*3)+(3*7)+(2*9)+(1*8)=135
135 % 10 = 5
So 140837-98-5 is a valid CAS Registry Number.
140837-98-5Relevant articles and documents
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
-
, (2016/05/09)
The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
USE OF t-BUTYL 4-DIETHYLPHOSPHONO-3-OXOBUTANETHIOATE FOR TETRAMIC ACID SYNTHESIS: TOTAL SYNTHESIS OF THE PLASMODIAL PIGMENT FULIGORUBIN A
Ley, Steven V.,Smith, Stephen C.,Woodward, Peter R.
, p. 5829 - 5832 (2007/10/02)
A short, efficient synthesis of the yellow slime mould pigment fuligorubin A (I) has been achieved using coupling of t-butyl 4-diethylphosphono-3-oxobutanethioate with deca-2,4,6,8-tetraenal and subsequent substitution with a glutamic acid derivative followed by Dieckmann cyclisation.
