140840-60-4Relevant academic research and scientific papers
A CONVENIENT SYNTHESIS OF 3(2)-TRIFLUOROACETYLAMINOBENZOTHIOPHENES AND THIOPHENES AND SOME OF THEIR IODO DERIVATIVES
Prats, Montserrat,Galvez, Carmen
, p. 149 - 156 (2007/10/02)
Trifluoroacetylamino derivatives of benzothiophene and thiophene (3a-d) have been obtained by Curtius rearrangement of the corresponding acyl azides (1a-d) with trifluoroacetic acid.The iodination of these amide derivatives with iodine under mild conditions leads to iodinated products in excellent yield, except in the case of the 3-trifluoroacetylaminobenzothiophene (3a), which only gives a polymeric residue.
