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1,2,3,4-tetrahydroisoquinolin-1-ylmethylamine dihydrochloride is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 140845-50-7 Structure
  • Basic information

    1. Product Name: 1,2,3,4-tetrahydroisoquinolin-1-ylmethylamine dihydrochloride
    2. Synonyms: (1,2,3,4-tetrahydroisoquinolin-1-ylmethyl)amine dihydrochloride;1,2,3,4-tetrahydroisoquinolin-1-ylmethanamine dihydrochloride;1,2,3,4-tetrahydroisoquinolin-1-ylmethylamine dihydrochloride;(1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)METHANAMINE 2HCL
    3. CAS NO:140845-50-7
    4. Molecular Formula: C10H14N2*2ClH
    5. Molecular Weight: 235.16
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 140845-50-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1,2,3,4-tetrahydroisoquinolin-1-ylmethylamine dihydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1,2,3,4-tetrahydroisoquinolin-1-ylmethylamine dihydrochloride(140845-50-7)
    11. EPA Substance Registry System: 1,2,3,4-tetrahydroisoquinolin-1-ylmethylamine dihydrochloride(140845-50-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 140845-50-7(Hazardous Substances Data)

140845-50-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 140845-50-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,8,4 and 5 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 140845-50:
(8*1)+(7*4)+(6*0)+(5*8)+(4*4)+(3*5)+(2*5)+(1*0)=117
117 % 10 = 7
So 140845-50-7 is a valid CAS Registry Number.

140845-50-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-aminomethyl-1,2,3,4-tetrahydroisoquinoline dihydrochloride

1.2 Other means of identification

Product number -
Other names 1-(AMINOMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE DIHYDROCHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:140845-50-7 SDS

140845-50-7Downstream Products

140845-50-7Relevant articles and documents

Novel molecular targeting anti-tumor aza-steroid derivative based on lipid toxicity and preparation and application thereof

-

Paragraph 0140; 0142; 0160; 0165; 0177, (2021/08/19)

The invention provides a novel molecular targeting anti-tumor aza-steroid derivative based on lipid toxicity and a preparation method and application thereof, and belongs to the field of chemical medicines. The derivative is a compound as shown in a formula I, or a salt thereof, or a stereoisomer thereof. The compound is low in toxicity or basically non-toxic to normal cells, has an obvious inhibition effect to tumor cell lines, particularly has good lipid toxicity selectivity to tumor cells such as liver cancer, lung cancer and the like in vivo, and has an obvious inhibition effect; meanwhile, the compound can effectively activate SREBP1 and PPAR gamma, inhibit lipid transport MTTP, cause lipid aggregation in tumor cells and cause lipid toxicity of the tumor cells. The compound can be used for treating liver cancer, lung cancer and the like in a molecular targeting manner, is low in toxicity or even non-toxic, and has a good application prospect.

Tetrazanbigen Derivatives as Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Partial Agonists: Design, Synthesis, Structure-Activity Relationship, and Anticancer Activities

Gan, Linling,Gan, Zongjie,Dan, Yanrong,Li, Yaowei,Zhang, Peiming,Chen, Shanwen,Ye, Zaijun,Pan, Tao,Wan, Chunmei,Hu, Xuelian,Yu, Yu

, p. 1018 - 1036 (2021/02/01)

Tetrazanbigen (TNBG) is a novel sterol isoquinoline derivative with poor water solubility and moderate inhibitory effects on human cancer cell lines via lipoapoptosis induction. Herein, we developed a series of novel TNBG analogues with improved water sol

Pyridinopyrazine compounds and preparation method thereof, and medical application of pyridinopyrazine compounds

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Paragraph 0049; 0055, (2016/10/07)

The invention relates to the field of pharmaceutical chemistry, particularly a series of pyridinopyrazine compounds (I). The pharmacodynamical test proves that the compounds are used for resisting external oxidation and electrophilic stimulation by activa

3-aroylmethylene-2,3,6,7-tetrahydro-1 H -pyrazino[2,1- a ]isoquinolin-4(11b H)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice

Xi, Mei-Yang,Jia, Jian-Min,Sun, Hao-Peng,Sun, Zhong-Ying,Jiang, Jie-Wei,Wang, Ya-Jing,Zhang, Min-Ye,Zhu, Jun-Feng,Xu, Li-Li,Jiang, Zheng-Yu,Xue, Xin,Ye, Ming,Yang, Xi,Gao, Yuan,Tao, Lei,Guo, Xiao-Ke,Xu, Xiao-Li,Guo, Qing-Long,Zhang, Xiao-Jin,Hu, Rong,You, Qi-Dong

, p. 7925 - 7938 (2013/11/06)

Nrf2-mediated activation of ARE regulates expression of cytoprotective enzymes against oxidative stress, inflammation, and carcinogenesis. We have discovered a novel structure (1) as an ARE inducer via luciferase reporter assay to screen the in-house data

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