140854-00-8

Basic information

• Product Name: Ethanone, 2,2,2-trifluoro-1-(3-methoxyphenyl)-, oxime, (E)-
• CAS NO: 140854-00-8
• Molecular Formula: C9H8F3NO2
• Molecular Weight: 219.163
• Mol File: 140854-00-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 2,2,2-trifluoro-1-(3-methoxyphenyl)-, oxime, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2,2,2-trifluoro-1-(3-methoxyphenyl)-, oxime, (E)-(140854-00-8)
• EPA Substance Registry System: Ethanone, 2,2,2-trifluoro-1-(3-methoxyphenyl)-, oxime, (E)-(140854-00-8)

Safety Data

• Hazardous Substances Data: 140854-00-8(Hazardous Substances Data)

Upstream product

• 2398-37-0 3-methoxyphenyl bromide 
• 591-20-8 3-Bromophenol 

Downstream Products

• 877667-26-0 3-(3-(trifluoromethyl)diazirin-3-yl)phenyl-9-oxo-9H-fluorene-2-carboxylate 
• 113787-85-2 3-(3-hydroxyhenyl)-3-(trifluoromethyl)-3H-diazirine 
• 1246216-22-7 C₂₀H₂₈BrF₃N₂O 
• 1246216-23-8 C₂₀H₂₉F₃N₂OS 
• 1246216-25-0 C₁₁H₁₁F₃O₃ 
• 1246216-27-2 C₁₆H₁₅F₃O₂ 
• 1246216-28-3 C₁₅H₁₃F₃O₂ 
• 1246216-29-4 C₁₆H₁₆F₃NO 
• 1246216-30-7 C₁₃H₁₃F₃O₃ 
• 1246216-31-8 C₁₇H₁₅F₃O 
• 1639939-95-9 C₁₁H₁₂F₃NO₂ 
• 1393743-80-0 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine 
• 1393743-78-6 3-(3-(6-iodohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine 
• 1393743-77-5 3-(3-(6-bromohexyloxy)phenyl)-3-(trifluoromethyl)-3H-diazirine 

Relevant articles and documents

CARBENE MASS TAGGING

The disclosure relates to a diazirine precursor mass tag compound represented by structural formula (I). Also disclosed is a method for detecting analytes in a sample, comprising derivatizing the analytes with the compound of formula (I), and detecting th

Diazirine-modified gold nanoparticle: Template for efficient photoinduced interfacial carbene insertion reactions

Photolysis of a 3-aryl-3-(trifluoromethyl)diazirine-modified monolayer-protected gold nanoparticles (2-C12MPNs), with a core size of 1.8 ± 0.3 nm, in the presence of model carbene trapping reagents leads to efficient, essentially quantitative, modification of the interface via carbene insertion reactions. The utility of carbene insertion reactions as a general approach for the modification of Au-MPNs to provide a breadth of new structures available was demonstrated using acetic acid, methanol, benzyl alcohol, phenol, benzylamine, methyl acrylate, and styrene (10a-g, respectively) as electrophilic carbene trapping agents to form the corresponding modified 3a-g-C12MPNs. The 1.8 ± 0.3 nm gold nanoparticles bearing a diazirine group (2-C12MPNs) were synthesized using the ligand exchange reaction with the requisite 3-aryl-3-(trifluoromethyl) diazirinealkylthiol. The 2-C12MPNs and the resulting products of the reaction on the MPN (3a-g-C12MPN) were fully characterized by IR, 1H NMR, and 19F NMR spectroscopy and, when applicable, transmission electron microscopy (TEM). Verification for the 3a-g-C 12MPNs was accomplished by comparison of the spectral data to those of obtained for the photoreactions of 3-(3-methoxyphenyl)-3-(trifluoromethyl)- 3H-diazirine as a model with 10a-g.

Aryldiazirine-modified pyroglutamates: Photoaffinity labels for glutamate

The synthesis of an aryldiazirine-modified pyroglutamate is reported for potential application as a photoaffinity label at glutamate receptors. Detailed 13C NMR and 19F NMR spectroscopic characterisation data for these trifluoromethy