14086-22-7

Usage

Uses

Used in Organic Synthesis:
EDTA-Bis-Hydrazide is used as a reagent for the preparation of functionalized hydrazides, which are essential intermediates in the synthesis of a wide range of organic compounds. Its unique structure and reactivity make it a valuable component in this application.
Used in Chemical Research:
1-(2,4-dinitrophenyl)-2-(2-ethylhexylidene)hydrazine is employed in chemical research to study its properties, reactivity, and potential applications in various fields. Its unique structure allows researchers to explore new reactions and mechanisms, contributing to the advancement of chemical science.
Used in the Development of New Materials:
EDTA-Bis-Hydrazide is used as a building block in the development of new materials, thanks to its versatile chemical properties. Its potential applications in this field include the creation of novel polymers, catalysts, and other advanced materials.
Used in Pharmaceutical Development:
1-(2,4-dinitrophenyl)-2-(2-ethylhexylidene)hydrazine is utilized in the pharmaceutical industry for the development of new drugs and drug candidates. Its unique structure and reactivity make it a promising starting point for the design and synthesis of new therapeutic agents.
Used in Agrochemical Development:
EDTA-Bis-Hydrazide is also used in the agrochemical industry for the development of new pesticides, herbicides, and other agricultural chemicals. Its potential applications in this field include the creation of more effective and environmentally friendly products.

Upstream product

• 149-57-5 2-Ethylhexanoic acid 
• 123-05-7 d,l-2-ethylhexanal 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 58735-67-4 2‐ethylhexanal 

Relevant academic research and scientific papers

Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes

The direct reduction of carboxylic acids to aldehydes is a fundamental transformation in organic synthesis. The combination of an air-stable Ni precatalyst, dimethyl dicarbonate as an activator, and silane reductant effects this reduction for a wide variety of substrates, including pharmaceutically relevant structures, in good yields and with no overreduction to alcohols. Moreover, this methodology is scalable, allows access to deuterated aldehydes, and is also compatible with one-pot utilization of the aldehyde products.

Unfunctionalized, α-epimerizable nonracemic ketones and aldehydes can be accessed by crystallization-induced dynamic resolution of imines

This paper describes an operationally simple deracemization process of aldehydes and ketones. This new crystallization-induced dynamic resolution (CIDR) protocol allows for nearly complete conversion of the racemic mixture into one enantiomer. Crystallization of imines derived from racemic ketones or aldehydes 1 and trans-(1R,2R)-1-amino-6-nitroindan-2-ol (2) afforded diastereomerically pure, crystalline imines 3. Biphasic hydrolysis of 3 then affords recovered 2 and enantiomerically enriched 1 in high yield and er (substrate, yield/ee: 2-methylcyclohexanone, 97%/92; 2-ethylhexanal, 94%/98; 2-methylcyclopentanone, 94%/98; 2-cyclohexylcyclohexanone, ND/98; 3-methyl-2-pentanone, ND/76). The scope, limitations, and industrial perspective of this process are discussed. This highly effective CIDR process is likely due to π-stacking of 2 and a hydrogen bonding of the imine with the free hydroxyl of 2 in the solid state. Copyright

Quantitative RP-HPLC determination of some aldehydes and hydroxyaldehydes as their 2,4-dinitrophenylhydrazone derivatives

A high-performance liquid chromatographic (HPLC) method is described for the quantitative determination of some aliphatic aldehydes and β- hydroxyaldehydes as their 2,4-dinitrophenylhydrazone derivatives. A method is described for the preparation of deriv