14088-64-3

Upstream product

• 936-65-2 α-hydroxymethylidenecyclooctanone 
• 1459-36-5 2-oxo-cyclooctanecarbaldehyde 
• 82734-47-2 2-trifluoroacetylcyclooctanone 
• 502-49-8 cycloactanone 

Downstream Products

• 99892-45-2 1-(1-Ethoxy-2-oxocyclooctyl)-4-phenyl-1,2,4-triazolidin-3,5-dion 
• 18208-28-1 Cycloheptan-carbonsaeure-anilid 
• 56631-64-2 2-(phenylsulfanyl)-2-cyclooctanene 
• 99892-48-5 4,4'-Bis<1-(1-ethoxy-2-oxocyclooctyl)-3,5-dioxo-1,2,4-triazolidin-4-yl>diphenylmethan 

Relevant academic research and scientific papers

Practical Application of the Aqueous 'Sulfonyl-Azide-Free' (SAFE) Diazo Transfer Protocol to Less α-C-H Acidic Ketones and Esters

The earlier described 'sulfonyl-Azide-free' ('SAFE') protocol for diazo transfer to CH-Acidic 1,3-dicarbonyl compounds (and their similarly activated congeners) has been extended to the less reactive monocarbonyl substrates, which previously required a se

Rhodium(II)- and copper(I)-catalyzed intramolecular carbon-hydrogen bond insertions with metal carbenoids derived from diazo ketones

The decomposition of diazo ketones in the presence of Rh(II) and Cu(I) catalysts affords products of C-H bond insertion in high yields. The effect of structural variation on intramolecular and transannular C-H insertions of diazo ketones has been investig

REGIOSPECIFIC SYNTHESIS OF α-(PHENYLTHIO)CYCLOALKENONES AND OF α-PHENYL-α-(PHENYLTHIO)KETONES VIA αα-ADDITION OF PHENYLSULPHENYL CHLORIDE TO α-DIAZOKETONES

Cyclic α-diazoketones react with phenylsulphenyl chloride at room temperature to furnish α-chloro-α-(phenylthio)cycloalkanones which undergo ready dehydrochlorination to α-(phenylthio)cycloalkenones when treated with triethylamine; acyclic, terminal α-diazoketones also furnish α-chloro-α-(phenylthio)adducts which are useful electrophiles in the synthesis of α-phenyl-α-(phenylthio)ketones.