140886-80-2Relevant academic research and scientific papers
SYNTHESIS AND REARRANGEMENT OF AMINOALKYL LACTONES TO SPIROCYCLIC HYDROXYMETHYL LACTAMS
Dostal, Claudia,Lauritz, Silvia,Urban, Ernst
, p. 135 - 148 (2007/10/02)
Lithiation of lactones (1) and (2) followed by electrophilic substitution with dibromoalkanes afforded bromoalkyl lactones (3a - 3c) and (4a - 4c).Treatment of 3a, 3b, 4a and 4b with primary amines led to formation of aminoalkyl lactones (5a, 5b, 6a, 6b a
