140896-85-1

Upstream product

• 1392467-20-7 1-(4-bromo-2-fluoro-phenyl)-2-methyl-propan-2-ol 
• 114897-92-6 2-(4-bromo-2-fluoro-phenyl)acetic acid 
• 193290-19-6 methyl 2-(4-bromo-2-fluoro-phenyl)acetate 
• 1203447-24-8 5-bromo-2-(2-methylallyl)phenol 
• 591-20-8 3-Bromophenol 
• 57469-91-7 1-(4-bromophenyl)-2-methyl-propan-2-ol 

Downstream Products

• 1243543-45-4 2,2-dimethyl-6-(4-methylphenyl)-2,3-dihydro-1-benzofuran 

Relevant academic research and scientific papers

TRPML MODULATORS

The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS

Compounds of Formula (0), Formula (I), and Formula (II) and methods of use as Interleukin-1 Receptor Associated Kinase (IRAK4) inhibitors are described herein.

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

Pd(II)-catalyzed hydroxyl-directed C-H activation/C-O cyclization: Expedient construction of dihydrobenzofurans

A Pd(II)-catalyzed C-H activation/C-O cyclization reaction directed by a proximate hydroxyl group has been developed. This reaction provides a new method for constructing dihydrobenzofurans, including spirocyclic analogues, a process that is potentially a

Benzofuran derivatives

The present invention provides a compound represented by the following formula (I): wherein: Ring A represents an optionally substituted piperazine ring, an optionally substituted morpholine ring, or an optionally substituted homopiperazine ring;R1 and R2 are the same or different from each other, and represent a hydrogen atom or optionally substituted lower alkyl;R3 and R4 are the same or different from each other, and represent a hydrogen atom or halogenated or non-halogenated lower alkyl;R5 to R7 are the same or different from each other, and represent a hydrogen atom, hydroxy, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkoxy, optionally substituted cycloalkyl, optionally substituted aryl, an optionally substituted aromatic heterocyclic ring, optionally substituted amino, or acyl; and represents a single bond or double bond, or a salt thereof.

Preparation of 2,2-disubstituted-2,3-dihydrobenzofurans

A process for the preparation of a 2,3-dihydrobenzofuran I STR1 or a derivative thereof, where Ra and Rb are C-organic radicals, involves reacting a 2-hydroxybenzyl alcohol II STR2 in the presence of an acidic ion exchanger resin and