140900-69-2

Upstream product

• 140900-71-6 methyl (1R,5S,6S,7R)-6-formyl-7-hydroxybicyclo<3.3.0>oct-2-ene-3-pentanoate 
• 140900-68-1 6-(3-azidophenyl)-1-(dimethoxyphosphoryl)-2-hexanone 
• 92356-69-9 methyl (2E,4E)-5-(3-nitrophenyl)-2,4-pentadienoate 
• 99-61-6 3-nitro-benzaldehyde 
• 88931-51-5 isocarbacyclin 
• 141887-77-6 5-(3-aminophenyl)pentanoic acid methyl ester 
• 141887-91-4 1-(dimethoxyphosphoryl)-6-(3-(tritylamino)phenyl)-2-hexanone 
• 141913-23-7 11,15-O-bisacetyl-13,14-epoxy-13,14-dihydroisocarbacyclin methyl ester 
• 141887-78-7 methyl 5-(3-tritylaminophenyl)pentanoate 
• 140900-70-5 13,14-dihydroxy-13,14-dihydroisocarbacyclin methyl ester 
• 141978-72-5 13,14-epoxy-13,14-dihydroisocarbacyclin methyl ester 

Downstream Products

• 141887-83-4 5-[(3aS,5R,6R,6aS)-5-Hydroxy-6-((E)-(S)-3-hydroxy-7-phenyl-hept-1-enyl)-1,3a,4,5,6,6a-hexahydro-pentalen-2-yl]-pentanoic acid methyl ester 
• 141887-84-5 5-[(1R,2R,3S,5R,6R,7R)-6-((E)-(S)-3-Hydroxy-7-phenyl-hept-1-enyl)-2-iodo-9-oxa-tricyclo[3.3.1.0^3,7]non-1-yl]-pentanoic acid methyl ester 
• 141887-96-9 5-{(3aS,5R,6R,6aS)-6-[(S)-7-(3-Amino-phenyl)-3-hydroxy-heptyl]-5-hydroxy-1,3a,4,5,6,6a-hexahydro-pentalen-2-yl}-pentanoic acid methyl ester 
• 141887-82-3 5-{(3aS,5R,6R,6aS)-6-[(E)-(S)-7-(3-Amino-phenyl)-3-hydroxy-hept-1-enyl]-5-hydroxy-1,3a,4,5,6,6a-hexahydro-pentalen-2-yl}-pentanoic acid methyl ester 
• 141887-98-1 5-[(1S,3S,4S,5R,7R)-4-((S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxymethyl)-9-oxa-tricyclo[3.3.1.0^3,7]non-1-yl]-pentanoic acid methyl ester 
• 141887-97-0 5-[(1R,2R,3S,5R,6S,7R)-2-Iodo-6-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxymethyl)-9-oxa-tricyclo[3.3.1.0^3,7]non-1-yl]-pentanoic acid methyl ester 
• 141887-85-6 5-{(1R,2R,3S,5R,6R,7R)-2-Iodo-6-[(E)-(S)-7-phenyl-3-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxy)-hept-1-enyl]-9-oxa-tricyclo[3.3.1.0^3,7]non-1-yl}-pentanoic acid methyl ester 
• 141887-99-2 5-[(3aS,5R,6R,6aS)-6-[(E)-(R)-7-(3-Azido-phenyl)-3-hydroxy-hept-1-enyl]-5-(tert-butyl-dimethyl-silanyloxy)-1,3a,4,5,6,6a-hexahydro-pentalen-2-yl]-pentanoic acid methyl ester 
• 141978-79-2 5-[(3aS,5R,6R,6aS)-6-[(E)-(S)-7-(3-Azido-phenyl)-3-hydroxy-hept-1-enyl]-5-(tert-butyl-dimethyl-silanyloxy)-1,3a,4,5,6,6a-hexahydro-pentalen-2-yl]-pentanoic acid methyl ester 
• 141887-95-8 5-{(3aS,5R,6R,6aS)-6-[(E)-(R)-7-(3-Azido-phenyl)-3-hydroxy-hept-1-enyl]-5-hydroxy-1,3a,4,5,6,6a-hexahydro-pentalen-2-yl}-pentanoic acid methyl ester 
• 141978-77-0 19-(3-azidophenyl)-20-norisocarbacyclin methyl ester 
• 141887-88-9 5-[(3aS,5R,6R,6aS)-6-[(E)-7-(3-Azido-phenyl)-3-oxo-hept-1-enyl]-5-(tert-butyl-dimethyl-silanyloxy)-1,3a,4,5,6,6a-hexahydro-pentalen-2-yl]-pentanoic acid methyl ester 

Relevant academic research and scientific papers

An azido-functionalized isocarbacyclin analogue acting as an efficient photoaffinity probe for a prostacyclin receptor

A stable prostacyclin analogue, (15S)-18c, having an azidophenyl group as a photoaffinity labeling functionality has been synthesized. This compound has a sufficiently high affinity to the prostacyclin receptor protein in mastocytoma P-815 cells, exhibiting an IC50 value of 3 nM for the replacement of iloprost bound to the receptor protein. A photoaffinity probe compound, [3H]-(15S)-18c, is obtainable by reduction of the ketone 16c with [3H]NaBH4 - CeCl3 followed by alkaline hydrolysis of the methyl ester.