140901-39-9

Basic information

• Product Name: C₃₈H₆₃O₁₄^(1-)*Na⁽¹⁺⁾
• CAS NO: 140901-39-9
• Molecular Weight: 766.9
• Mol File: 140901-39-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₈H₆₃O₁₄^(1-)*Na⁽¹⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₈H₆₃O₁₄^(1-)*Na⁽¹⁺⁾(140901-39-9)
• EPA Substance Registry System: C₃₈H₆₃O₁₄^(1-)*Na⁽¹⁺⁾(140901-39-9)

Safety Data

• Hazardous Substances Data: 140901-39-9(Hazardous Substances Data)

Upstream product

• 101693-34-9 C₅₂H₈₇O₁₈^(1-)*Na⁽¹⁺⁾ 

Relevant articles and documents

Synthetic modification of a novel microbial ionophore: Exploration of anticoccidial structure-activity relationships

While fermentation-derived polyether ionophores such as salinomycin are the dominant class of anticoccidial feed additives, there is little information concerning the structural features which confer optimal potency/efficacy in this important series. The recently discovered microbial polyether 1a, featuring potent, broad-spectrum anticoccidial activity, was employed as a template to explore structure-activity relationships. A number of single-step synthetic modifications targeted structural changes in both the lipophilic carbon backbone and the ion-binding cavity of 1a. Although previous semisynthetic transformations among the polyether ionophores almost always resulted in a substantial loss of anticoccidial activity, we obtained several analogues, altered on the periphery of the ionophore-ion complex, which retain good potency and efficacy. Monoglycone 7 (semduramicin sodium) has the most impressive anticoccidial profile of this series, and is undergoing further biological testing under field conditions.