140902-67-6

Basic information

• Product Name: Cyclohexanol, 1-[(2-hydroxy-2-methylcyclopentyl)methyl]-, trans-
• CAS NO: 140902-67-6
• Molecular Formula: C13H24O2
• Molecular Weight: 212.332
• Mol File: 140902-67-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclohexanol, 1-[(2-hydroxy-2-methylcyclopentyl)methyl]-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanol, 1-[(2-hydroxy-2-methylcyclopentyl)methyl]-, trans-(140902-67-6)
• EPA Substance Registry System: Cyclohexanol, 1-[(2-hydroxy-2-methylcyclopentyl)methyl]-, trans-(140902-67-6)

Safety Data

• Hazardous Substances Data: 140902-67-6(Hazardous Substances Data)

Upstream product

• 21889-88-3 hept-6-en-2-one 
• 108-94-1 cyclohexanone 

Relevant articles and documents

Samarium(II) Iodide-Induced Reductive Cyclization of Unactivated Olefinic Ketones. Sequential Radical Cyclization/Intermolecular Nucleophilic Addition and Substitution Reactions

Samarium(II) iodide in the presence of HMPA effectively promotes the intramolecular coupling of unactivated olefinic ketones by a reductive ketyl-olefin radical-cyclization process.The reaction is quite general for the formation of 5- and 6-membered carbocycles and even provides modest yields in less facile cyclization processes as evidenced by the generation of methylcyclooctanol via an 8-endo cyclization.Sequential radical cyclization-intermolecular nucleophilic addition/substitution processes set the SmI2 reaction apart from its radical-chain, photochemical, and electrochemical counterparts.In addition to delineating the synthetic potential of this reaction, the role played by HMPA in enhancing SmI2 reactivity has been further refined, and a model correlating the high diastereoselectivity and product distribution in SmI2-promoted reductive coupling processes with HMPA concentration has been established.