140903-39-5Relevant academic research and scientific papers
Synthesis of α-amino dithioesters and endothiodipeptides
Hartke, Klaus,Barrmeyer, Stephan
, p. 251 - 256 (2007/10/03)
The α-amino ester hydrochlorides (1) are converted into N-protected α-amino amides (3), α-amino thioamides (4) and α-amino dithiomethylesters (5). Condensation of 5 with the alkali salts of α-amino acids gives rise to the endothiodipeptide alkali salts (7). Johann Ambrosius Barth 1996.
Dithio and Thiono Esters, 53. Synthesis of N-Protected α-Amino Dithioesters from α-Amino Nitriles and α-Amino Acids
Kohrt, Arne,Hartke, Klaus
, p. 595 - 606 (2007/10/02)
The α-Amino nitriles 1 and 5 have been transformed into the thiolimido ester hydrochlorides 2 and 6 and sulfhydrolyzed to give the N-protected α-amino dithioesters 3 and 7.The α-amino dithioesters 10 were obtained from 1 via the thioamides 8 and their S-a
