1409963-20-7Relevant articles and documents
DIPHENYL DERIVATIVES AND USES THEREOF
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Paragraph 1150-1151, (2019/03/30)
The present disclosure provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, and its therapeutic uses for activating a growth factor pathway, promoting wound healing, promoting tissue repair, and treating hearing loss, skeletal muscle loss, organ degeneration, tissue damage, neurodegeneration, and muscular atrophy. The disclosure further provides pharmaceutical compositions and combinations. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
Facile, diversity-orientated one-pot synthesis of ethyl 1,5-disubstituted-1H-1,2,4-triazole-3-carboxylates
Degorce, Sébastien,Delouvrié, Bénédicte,Davey, Paul R.J.,Didelot, Myriam,Germain, Hervé,Harris, Craig S.,Brempt, Christine Lambert-Van Der,Lebraud, Honorine,Ouvry, Gilles
supporting information, p. 6078 - 6082 (2012/11/07)
Access to the 1,5-disubstituted-1H-1,2,4-triazole-3-carboxamide motif is quite laborious and requires forcing conditions to effect the cyclocondensation step. Herein, we report an efficient and mild one-pot protocol to access this substructure in good che