1410163-76-6Relevant academic research and scientific papers
Iron-Catalyzed Intermolecular Hydrothiolation of Internal Alkynes with Thiosalicylic Acids, and Sequential Intramolecular Cyclization Reaction
Sonehara, Taro,Murakami, Shogo,Yamazaki, Sae,Kawatsura, Motoi
, p. 4299 - 4302 (2017)
We demonstrate the iron-catalyzed intermolecular coupling of internal alkynes and thiosalicylic acid derivatives. The reaction was effectively catalyzed by the Fe(acac)2/1,10-phenanthroline catalyst in toluene/HFIP (hexafluoroisopropyl alcohol)
Hydrothiolation and intramolecular cyclization sequence for the synthesis of 1,3-oxathiine frameworks
Nishina, Yuta,Miyata, Junya
experimental part, p. 2607 - 2613 (2012/09/07)
1,3-Oxathiine frameworks can be prepared via the sequential addition and intramolecular cyclization of thiosalicylic acid onto alkynes. A substituent on the alkyne and the presence of a palladium catalyst can allow product regioselectivity control. This strategy is applicable to the synthesis of heterocycles comprising sulfur and oxygen atoms, namely 3,1-benzoxathiines, without any unwanted byproduct. Georg Thieme Verlag Stuttgart · New York.
