14102-77-3

Upstream product

• 115118-19-9 (E)-4-((1R,2S)-2-Phenyl-1,2-dihydro-4,6-dioxa-cyclobuta[f]inden-1-yloxycarbonylamino)-but-2-enoic acid methyl ester 
• 115118-20-2 (E)-4-((1R,2S)-2-Phenyl-1,2-dihydro-4,6-dioxa-cyclobuta[f]inden-1-yloxycarbonylamino)-but-2-enoic acid 
• 107377-40-2 (1R,2S)-2-Phenyl-1,2-dihydro-4,6-dioxa-cyclobuta[f]inden-1-ol 
• 107377-31-1 3-(6-Bromo-benzo[1,3]dioxol-5-yl)-3-phenyl-propionic acid ethyl ester 
• 115140-89-1 3-(6-Bromo-benzo[1,3]dioxol-5-yl)-3-phenyl-propionic acid 
• 107377-34-4 2-Phenyl-1,2-dihydro-4,6-dioxa-cyclobuta[f]indene-1-carboxylic acid ethyl ester 
• 107377-37-7 trans-2-phenyl-4,5-(methylenodioxy)benzocyclobutene-1-carboxylic acid 

Relevant academic research and scientific papers

A Highly Stereoselective Synthesis of Podophyllotoxin and Analogues Based on an Intramolecular Diels-Alder Reaction

A synthesis of podophyllotoxin and several analogues is described.The key step that generates all four chiral centers of podophylotoxin involves an intramolecular Diels-Alder reaction between an appropriately substituted o-quinodimethane and a pendant cro