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N,N'-Bis(2-bromoethyl)phosphorodiamidic acid, commonly referred to as BBEPDA, is a phosphorodiamidic acid derivative with the molecular formula C6H12Br2N2O2P. It is a white solid at room temperature, soluble in polar organic solvents, and is known for its ability to form complexes with metal ions. BBEPDA is utilized as a reagent in organic synthesis and is involved in various chemical reactions, including coupling and cross-coupling reactions. It also plays a role in the synthesis of pharmaceuticals and agrochemicals. However, due to its toxic nature, BBEPDA requires careful handling to prevent ingestion, inhalation, or skin and eye irritation.

141025-16-3

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141025-16-3 Usage

Uses

Used in Organic Synthesis:
N,N'-Bis(2-bromoethyl)phosphorodiamidic acid is used as a reagent in organic synthesis for its ability to form complexes with metal ions, facilitating various chemical reactions such as coupling and cross-coupling reactions.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, BBEPDA is used as a key intermediate in the synthesis of certain drugs, contributing to the development of new medicinal compounds.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical sector, BBEPDA serves as an essential component in the synthesis of various agrochemicals, aiding in the production of substances that protect crops and enhance agricultural productivity.

Check Digit Verification of cas no

The CAS Registry Mumber 141025-16-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,0,2 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 141025-16:
(8*1)+(7*4)+(6*1)+(5*0)+(4*2)+(3*5)+(2*1)+(1*6)=73
73 % 10 = 3
So 141025-16-3 is a valid CAS Registry Number.

141025-16-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name bis(2-bromoethylamino)phosphinic acid

1.2 Other means of identification

Product number -
Other names N,N'-Bis(2-bromoethyl)phosphoric acid diamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141025-16-3 SDS

141025-16-3Downstream Products

141025-16-3Relevant academic research and scientific papers

TH-302 SOLID FORMS AND METHODS RELATED THERETO

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Paragraph 0053; 0102, (2016/02/10)

The present invention provides a new method for making TH-302 and solid forms thereof. The compound in its solid form is an effective anti-cancer agent and may be used in various pharmaceutical compositions, and are particularly effective for the treatment of cancer. The invention also provides a method for preparing such compounds and forms and for treating cancer in a mammal comprising the step of administering a therapeutically effective amount of a solid form of TH-302 thereof.

TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS

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Page/Page column 36, (2010/11/17)

The invention relates to novel compounds for use in the treatment or prophylaxis of cancers and other proliferative conditions that are for example characterized by cells that express cytochrome P450 1B1 (CYP1B1) and allelic variants thereof. The invention also provides pharmaceutical compositions comprising one or more such compounds for use in medical therapy, for example in the treatment of prophylaxis of cancers or other proliferative conditions, as well as methods for treating cancers or other conditions in human or non-human animal patients. The invention also provides methods for identifying novel compounds for use in the treatment of prophylaxis of cancers and other proliferative conditions that are for example characterized by cells that express CYP1 B1 and allelic variants thereof. The invention also provides a method for determining the efficacy of a compound of the invention in treating cancer.

PHOSPHORAMIDATE ALKYLATOR PRODRUGS

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Page/Page column 125-126, (2008/06/13)

Phosphoramidate alkylator prodrugs can be used to treat cancer when administered alone or in combination with one or more anti-neoplastic agents.

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