141033-59-2Relevant academic research and scientific papers
Utilization of O-xylylene N,N-diethylphosphoramidite for the synthesis of phosphoric diesters
Watanabe, Yutaka,Komoda, Yasunobu,Ozaki, Shoichiro
, p. 1313 - 1316 (2007/10/02)
o-Xylylene alkyl phosphites which were derived by the reaction of alcohols with o-xylylene N,N-diethylphosphoramidite in the presence of 1H-tetrazole were reacted with second alcohols in the presence of pyridinium bromide perbromide, and a tert-amine, to give the corresponding triesters involving phospholipids. The esters were deprotected to phosphoric diesters by hydrogenolysis or the reaction with disodium disulfide.
