141045-67-2

Upstream product

• 141045-64-9 (2S,1'S,2'S)-N-(Benzyloxycarbonyl)-2-<1'-hydroxy-2'-(phenylthio)-3'-butenyl>pyrrolidine 
• 141045-65-0 (2S,1'S,2'S)-N-(Benzyloxycarbonyl)-2-<1'-acetoxy-2'-(phenylthio)-3'-butenyl>pyrrolidine 
• 501-53-1 benzyl chloroformate 
• 71461-30-8 (S)-2-formylpyrrolidine-1-carboxylic acid benzyl ester 
• 6216-63-3 N-Cbz-Prolinol 
• 141045-66-1 (2S,1'R)-N-(Benzoxycarbonyl)-2-(1'-acetoxy-4'-hydroxy-2'-butenyl)pyrrolidine 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 141045-69-4 (2S,1'S,2'S,3'S)-N-(Benzoxycarbonyl)-2-<1'-acetoxy-2',3'-O-isopropylidene-2',3'-dihydroxy-4'-<(tert-butyldiphenylsilyl)oxy>butyl>pyrrolidine 
• 141045-68-3 (2S,1'S,2'R,3'S)-N-(Benzoxycarbonyl)-2-<1'-acetoxy-2',3'-dihydroxy-4'-<(tert-butyldiphenylsilyl)oxy>butyl>pyrrolidine 
• 141045-68-3 (2S,1'S,2'R,3'R)-N-(Benzoxycarbonyl)-2-<1'-acetoxy-2',3'-dihydroxy-4'-<(tert-butyldiphenylsilyl)oxy>butyl>pyrrolidine 

Relevant academic research and scientific papers

Synthesis of 1-Deoxycastanospermin and Stereoisomers

Four different isomers of 1-deoxycastanospermine (6,7,8-trihydroxyindolizidine) were synthesized.Their basic skeleton was constructed from a proline derivative and the anion of allyl phenyl sulfide, followed by an allylic sulfide rearrangement and a subsequent nucleophilic cyclization.The aminotriols were obtained in good yields with a concise overall sequence.