141064-23-5 Usage
Description
Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline (oxalate) is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively). It has antipsychotic-like activities in rats and Cebus monkeys. M1 selective agonists, like Xanomeline (oxalate), enhance memory function and has utility in treating Alzheimer’s Disease.
Uses
Xanomeline oxalate is a functionally selective mAChR M1 agonist.
Check Digit Verification of cas no
The CAS Registry Mumber 141064-23-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,0,6 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 141064-23:
(8*1)+(7*4)+(6*1)+(5*0)+(4*6)+(3*4)+(2*2)+(1*3)=85
85 % 10 = 5
So 141064-23-5 is a valid CAS Registry Number.
141064-23-5Relevant articles and documents
METHOD OF TREATING SCHIZOPHRENIA
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, (2008/06/13)
The present invention relates to a novel method for treating a mammal suffering from or susceptible to schizophrenia and schizophreniform diseases by administering thiadiazole or oxadiazole compounds.
Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives
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, (2008/06/13)
The present invention relates to a novel method for treating a mammal suffering from urinary bladder dysfunctions.
Piperidine compounds and their preparation and use
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, (2008/06/13)
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebra