141069-36-5Relevant academic research and scientific papers
A novel stereoselective route to γ-butyrolactones
Casey,Manage,Murphy
, p. 965 - 968 (1992)
Treatment of the products obtained from conjugate additions of sulfoxides to α,β-unsaturated carbonyl compounds with soft electrophiles resulted in intramolecular displacement of the sulfinyl group by the carbonyl to give γ-butyrolactones. This novel cyclisation works best for benzylic sulfoxides and provides a concise route to trans-β,γ-disubstituted lactones with high stereoselectivity.
