141074-06-8Relevant articles and documents
PROCESS FOR PREPARING PROSTAGLANDIN DERIVATIVES
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Paragraph 110-112, (2010/10/03)
The present invention relates to a process for preparing a prostaglandin derivative and an intermediate therefor. In accordance with the present invention, the prostaglandin F (PGF) derivative can be efficiently prepared with high purity by removing the protecting group of a protected prostaglandin E (PGE) derivative obtained from conjugate addition and then stereoselectively reducing the ketone group on the cyclopentanone ring of the PGE derivative.