1410791-81-9

Basic information

• Product Name: ethyl 2-(((benzyloxy)carbonyl)(hydroxy)amino)-2-methyl-3-oxo-4-phenylbutanoate
• Synonyms: ethyl 2-(((benzyloxy)carbonyl)(hydroxy)amino)-2-methyl-3-oxo-4-phenylbutanoate
• CAS NO: 1410791-81-9
• Molecular Weight: 385.417
• Mol File: 1410791-81-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-(((benzyloxy)carbonyl)(hydroxy)amino)-2-methyl-3-oxo-4-phenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(((benzyloxy)carbonyl)(hydroxy)amino)-2-methyl-3-oxo-4-phenylbutanoate(1410791-81-9)
• EPA Substance Registry System: ethyl 2-(((benzyloxy)carbonyl)(hydroxy)amino)-2-methyl-3-oxo-4-phenylbutanoate(1410791-81-9)

Safety Data

• Hazardous Substances Data: 1410791-81-9(Hazardous Substances Data)

Upstream product

• 3426-71-9 Benzyl N-hydroxycarbamate 
• 2867-62-1 ethyl 2-methyl-3-oxo-4-phenylbutanoate 

Relevant articles and documents

Electrophilic α-amination reaction of β-ketoesters using N -hydroxycarbamates: Merging aerobic oxidation and lewis acid catalysis

The copper-catalyzed α-amination of carbonyl compounds using nitrosoformate intermediates as the electrophilic source of nitrogen is reported. The reaction merges aerobic oxidation and Lewis acid catalysis. The scope of the reaction is broad in terms of both the N-substituted hydroxylamines and the β-ketoesters. The new methodology harnesses the power of nitrosoformate intermediates and demonstrates their potential as a viable electrophilic source of nitrogen in α-functionalization reactions.