141081-81-4

Basic information

• Product Name: ((R)-Toluene-4-sulfinyl)-acetic acid (S)-4-oxo-2-(toluene-4-sulfonyloxymethyl)-butyl ester
• Synonyms: ((R)-Toluene-4-sulfinyl)-acetic acid (S)-4-oxo-2-(toluene-4-sulfonyloxymethyl)-butyl ester
• CAS NO: 141081-81-4
• Molecular Weight: 452.549
• Mol File: 141081-81-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ((R)-Toluene-4-sulfinyl)-acetic acid (S)-4-oxo-2-(toluene-4-sulfonyloxymethyl)-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((R)-Toluene-4-sulfinyl)-acetic acid (S)-4-oxo-2-(toluene-4-sulfonyloxymethyl)-butyl ester(141081-81-4)
• EPA Substance Registry System: ((R)-Toluene-4-sulfinyl)-acetic acid (S)-4-oxo-2-(toluene-4-sulfonyloxymethyl)-butyl ester(141081-81-4)

Safety Data

• Hazardous Substances Data: 141081-81-4(Hazardous Substances Data)

Upstream product

• 141081-72-3 (Rs)-2,2-dimethyl-5-<3-oxo-4-(p-tolylsulfinyl)butyl>-1,3-dioxane 
• 141081-73-4 1-((R)-Toluene-4-sulfinylmethyl)-2,6-dioxa-bicyclo[2.2.2]octane 
• 141096-58-4 5-<2-(ethoxycarbonyl)ethyl>-2,2-dimethyl-1,3-dioxane 
• 141081-71-2 (E)-5-<2-(ethoxycarbonyl)ethenyl>-2,2-dimethyl-1,3-dioxane 
• 141081-78-9 (3S,Rs)-<3,4-dihydro-6-(p-tolylsulfinyl)methyl-2H-pyran-3-yl>methyl p-toluenesulfonate 

Downstream Products

• 141081-83-6 (3R,Rs)-3-<(p-tolylsulfinyl)acetoxymethyl>butan-4-olide 

Relevant articles and documents

Asymmetric desymmetrization of prochiral 1,3-diols via diastereoselective C-O bond fission of bicyclic acetal using a chiral sulfoxide as a chiral auxiliary

Asymmetric desymmetrization of a prochiral 1,3-diol was established by diastereoselective C-O bond fission of the chiral α-sulfinyl acetal 6. Treatment of 6 with titanium tetrachloride afforded mainly 7a via an oxonium intermediate, while with lithium diisopropylamide 7b was selectively obtained via diastereoselective β-elimination followed by an olefin isomerization.