1410916-65-2Relevant academic research and scientific papers
Synthesis of 3-substituted 4-alkoxyisoquinolin-1-amines by the reaction of 2-[alkoxy(lithio)methyl]-benzonitriles with nitriles
Kobayashi, Kazuhiro,Matsumoto, Kota,Ezaki, Kosuke
, p. 2523 - 2529,7 (2020/08/24)
It has been found that the reaction of 2-[alkoxy(lithio)methyl] benzonitriles, generated in situ from 2-(alkoxymethyl)benzonitriles and two equivalents of lithium diisopropylamide in diglyme at -78 °C, with aliphatic and aromatic nitriles provides an effi
