141104-29-2Relevant academic research and scientific papers
A NOVEL SYNTHESIS OF 4-METHYL-, 4-OXO-, AND 4-AMINO-3-(3-METHYL-5-ISOXAZOLYL)PYRIDINE DERIVATIVES VIA N-SILYL-1-AZA-ALLYL ANION
Konakahara, Takeo,Sugama, Naoki,Sato, Kenji
, p. 157 - 160 (2007/10/02)
An N-silyl-aza-allyl anion (1) reacted with alkoxyalkenes (3a)-(3e) to afford the corresponding 4-methyl-pyridines (4a) and (4b), 4-pyridones (5c) and (5d), and 4-amino-pyridine (4e), possessing a 3-methyl-5-isoxazolyl group on C-3 atom, in 91, 90, 62, 27, and 68percent yields, respectively, whereas alkoxyalkenes (3f) and (3g) gave the corresponding N-adduct intermediates (6f) and (6g) in 46 and 60percent yields.
