141104-65-6Relevant articles and documents
Synthesis of indan-based unusual α-amino acid derivatives under phase-transfer catalysis conditions
Kotha, Sambasivarao,Brahmachary, Enugurthi
, p. 1359 - 1365 (2000)
Conformationally constrained cyclic a-amino acid derivatives were synthesized under solid-liquid phase-transfer catalysis conditions. This methodology involves the bis-alkylation of ethyl isocyanoacetate with various a,a'-dibromo-o-xylene derivatives [a,a'-dibromo-o-xylene 5, 2,3-bis(bromomethyl)-l,4-dimethoxybenzene 6, l,2-bis(bromomethyl)-4,5-dibromobenzene 7,2,3-bis(bromomethyl)naphthalene 8, l,8-bis(bromomethyl)-naphthalene 9, 6,7-bis(bromomethyl)-2,2-dimethyl-lJ/phenalene-l,3(2H)-dione 10,2,3-bis(bromomethyl)-l,4-anthraquinone 11,6,7-bis(bromomethyl)quinoxaline 12, 3,4-bis(bromomethyl)furan 13, l,2,4,5-tetrakis(bromomethyl)benzene 28, and hexakis(bromomethyl)benzene 30] using potassium carbonate as a base and tetrabutylammonium hydrogensulfate as a phase-transfer catalyst to give corresponding isonitrile derivatives, which upon hydrolysis with HC1 in ethanol gave amino esters. Using this method electron-deficient as well as electron-rich and halogen-substituted indan-based a-amino acids were prepared. The preparation of bis-indan as well as tris-indan a-amino esters is also described.
Organic crystal engineering with piperazine-2,5-diones. 1. Crystal packing of piperazinediones derived from substituted 2-aminoindan-2- carboxylic acids
Williams, Lawrence J.,Jagadish,Lyon, Scott R.,Kloster, Robin A.,Carducci, Michael D.,Mash, Eugene A.
, p. 14281 - 14300 (2007/10/03)
We have postulated that molecules engineered to participate in three chemically distinct and linearly independent intermolecular interactions will self-assemble in a predictable fashion. Six prototypes for molecules capable of manifesting such interaction