1411775-05-7

Upstream product

• 1252018-16-8 4-{4-[(5S)-5-chloromethyl-2-oxo-1,3-oxazoIidine-3-yl]-phenyl}-morpholine-3-one 
• 1252018-21-5 (S)-4-[4-[(3-chloro-2-hydroxypropyl)amino]phenyl]-3-morpholinone 
• 438056-69-0 4-(4-aminophenyl)morpholin-3-one 
• 1252018-18-0 4-{4-[5(S)-iodomethyl-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morpholine-3-one 
• 103-49-1 dibenzylamine 

Downstream Products

• 1411775-07-9 4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate 
• 865479-71-6 5-chloro-N-({(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide 

Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS

The invention relates to a process for the preparation of 5-chloro- N- ({(5-S)-2-oxo3-[4-(3-oxo-morj)holine-4-yl)-phenyl]-l,3-oxazolidine-5-yl}-methyl) thiophen-2-carboxamide having the INN rivaroxaban. The process is characterized by the reactions according to claim 1. The invention also relates to intermediates formed in the above process.