14119-75-6 Usage
Uses
Used in Pharmaceutical Research:
1-(3-methyl-1H-indol-2-yl)pyridinium is used as a key intermediate in the synthesis of various pharmaceutical compounds due to its potential applications in drug development. Its unique chemical properties facilitate reactions such as alkylation and Friedel-Crafts acylation, which are crucial in the creation of novel therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(3-methyl-1H-indol-2-yl)pyridinium serves as a valuable building block for the construction of complex molecular structures. Its reactivity and structural features make it a preferred choice for the synthesis of a wide range of organic compounds.
Used in Medicinal Chemistry:
1-(3-methyl-1H-indol-2-yl)pyridinium is used as a subject of study in medicinal chemistry for its potential pharmacological activities. It has been explored for its anti-inflammatory and antitumor properties, making it an interesting target for the development of new drugs to treat various diseases.
Used in Drug Development:
1-(3-methyl-1H-indol-2-yl)pyridinium is also used as a starting material or a scaffold in drug development. Its structural versatility allows for the creation of new molecules with potential therapeutic benefits, contributing to the advancement of pharmaceutical research and innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 14119-75-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,1,1 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14119-75:
(7*1)+(6*4)+(5*1)+(4*1)+(3*9)+(2*7)+(1*5)=86
86 % 10 = 6
So 14119-75-6 is a valid CAS Registry Number.
14119-75-6Relevant academic research and scientific papers
Syntheses and characterization of N-(Indolyl)pyridinium salts and of their ylides
Pidlypnyi, Nazar,Kaul, Sandra,Wolf, Sebastian,Drafz, Martin H.H.,Schmidt, Andreas
, p. 605 - 614 (2014/06/10)
3-Methylindole reacts with pyridines in the presence of NBS to give indol-2-yl-pyridinium salts which were converted into their ylides by an anion exchange resin in its hydroxide form. Indol-3-amine was subjected to a nucleophilic ring transformation with pyrylium salts which resulted in the formation of indol-3-yl-pyridinium salts, the 2,4,6-trimethylpyridinium derivative of which proved to be unstable. The 2,4,6-triphenylpyridinium derivate was deprotonated to the corresponding ylide. The isomeric indol-2-yl and indol-3-yl derivatives are cycloimmonium ylides which are members of the compound class of heterocyclic mesomeric betaines (MB). By contrast, the ylide of indol-2-yl-pyrrolidinium is a cycloammonium ylide. It was prepared by reaction of 3-methylindole with pyrrolidine in the presence of NBS, followed by deprotonation.
