141195-16-6

Upstream product

• 1191-99-7 2,3-dihydro-2H-furan 
• 3857-83-8 2-naphthyl triflate 
• 141077-52-3 3,4-dimethoxyphenyl trifluoromethanesulfonate 
• 124244-44-6 2-(naphthalen-2-yl)-2,3-dihydrofuran 

Downstream Products

• 112068-06-1 trans-(R,R)-2-(2-naphthyl)-5-(3,4-dimethoxyphenyl)tetrahydrofuran 
• 112068-07-2 trans-(S,S)-2-(2-naphthyl)-5-(3,4-dimethoxyphenyl)tetrahydrofuran 

Relevant academic research and scientific papers

Kinetic resolution of 2-substituted-2,3-dihydrofurans by a palladium-catalyzed asymmetric Heck reaction

The kinetic resolution of 2-substituted-dihydrofurans via a palladium-catalyzed asymmetric Heck reaction was realized, providing optically active 2-substituted-dihydrofurans and trans-2,5-disubstituted-dihydrofurans in high yield and good enantioselectivities with an S factor up to 70.

Palladium-catalyzed asymmetric arylation of 2,3-dihydrofuran: 1,8-Bis(dimethylamino)naphthalene as an efficient base

Reaction of 2,3-dihydrofuran with aryl triflate (1) in the presence of a base and a palladium catalyst, generated in situ from Pd(OAc)2 and (R)-BINAP, gave (R)-2-aryl-2,3-dihydrofuran (2) and a small amount of (S)-2-aryl-2,5-dihydrofuran (3). T