141208-49-3

Basic information

• Product Name: Cyclobutanecarboxylic acid, 2,3-bis(hydroxymethyl)-, [1S-(1alpha,2alpha,3beta)]- (9CI)
• Synonyms: Cyclobutanecarboxylic acid, 2,3-bis(hydroxymethyl)-, [1S-(1alpha,2alpha,3beta)]- (9CI)
• CAS NO: 141208-49-3
• Molecular Formula: C7H12O4
• Molecular Weight: 160.16778
• Product Categories: CARBOXYLICACID
• Mol File: 141208-49-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclobutanecarboxylic acid, 2,3-bis(hydroxymethyl)-, [1S-(1alpha,2alpha,3beta)]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutanecarboxylic acid, 2,3-bis(hydroxymethyl)-, [1S-(1alpha,2alpha,3beta)]- (9CI)(141208-49-3)
• EPA Substance Registry System: Cyclobutanecarboxylic acid, 2,3-bis(hydroxymethyl)-, [1S-(1alpha,2alpha,3beta)]- (9CI)(141208-49-3)

Safety Data

• Hazardous Substances Data: 141208-49-3(Hazardous Substances Data)

Upstream product

• 141208-45-9 (3S,4S)-3,4-bisbenzyloxymethyl-2-diazo-1-cyclopentanone 
• 96055-60-6 (3S,4S)-3,4-bis-(-)-menthyloxycarbonyl-1-methylidenecyclopentane 
• 141208-46-0 methyl (1RS,2R,3S)-2,3-bisbenzyloxymethylcyclobutane-1-carboxylate 
• 141208-44-8 (3S,4S)-3,4-bisbenzyloxymethyl-1-cyclopentanone 
• 141208-43-7 (3S,4S)-3,4-bisbenzyloxymethyl-1-methylidenecyclopentane 
• 138804-28-1 (3S,4S)-3,4-bishydroxymethyl-1-methylidenecyclopentane 
• 141208-48-2 (1RS,2R,3S)-2,3-bisbenzyloxymethylcyclobutane-1-carboxylic acid 

Relevant articles and documents

A Facile Enantioselective Synthesis of (1R,2R,3S)-1-Amino-2,3-bishydroxymethylcyclobutane Derivatives, A Key Synthetic Intermediate of Carbocyclic Oxetanocins

(1R,2R,3S)-1-Amino-2,3-bishydroxymethylcyclobutane derivatives (14, 15) have been synthesized enantioselectively by formation of a cyclopentane ring from (-)-dimenthyl succinate and 3-chloro-2-(chloromethyl)-1-propene and the subsequent ring contrac